STUDIES OF THE EFFECT OF COMBINED USE OF CYCLOPHOSPHAMIDE AND DEANOL ACETYLGLUMAT ON SOME PARAMETERS OF THE CELLULAR COMPOSITION OF VENOUS BLOOD AND HEMATOSIS OF RABBITS

Kustikova Irina Nikolaevna, Senior lecturer, sub-department of general and clinical pharmacology, Medical institute, Penza State University, pgu_farm@mail.ru
Moiseeva Inessa Yakovlevna, Doctor of medical sciences, professor, head of sub-department of general and clinical pharmacology, Medical institute, Penza State University, moiseeva_pharm@mail.ru
Ionicheva Lyubov Vladimirovna, Candidate of medical sciences, associate professor, human physiology sub-department, Medical institute, Penza State University, pgu_farm@mail.ru
Burko Pavel Alexandrovich, Student, Medical institute, Penza State University, pgu_farm@mail.ru

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Results of research of influence deanola aceglumate on leukocytic structure of venous blood and leukopoiesis the rabbits, a course of antineoplastic therapy applied against modelling cyclophosphamide are stated. It is shown, that application deanola aceglumate in the given mode of introduction reduces consequences of toxic influence cyclophosphamide on leukopoies. However maintenance of cellular struc-ture of blood is accompanied by tension hematosis and braking proliferative and dif-ferentiation processes in granulocytic to a pool hematopoietic a bone brain.

оncology, cyclophosphamide, deanola aceglumate, antioxidant, spongy bone.